Prevention and Treatment of Cerebrovascular Disease

Update Item Information
Identifier 20130211_nanos_journalclubsympos_04-2
Title Prevention and Treatment of Cerebrovascular Disease
Creator Renee B. Van Stavern
Subject Acute Stroke; Atrial Fibrillation; Carotid Stenosis; Intracranial Arteriosclerosis; Patent Foramen Ovale
Description Intravenous thrombolysis with alteplase (Genentech; San Francisco, CA) is the only FDA approved treatment for acute ischemic stroke when administered fewer than 3 hours after the onset of symptoms. The European Cooperative Acute Stroke Study-III (ECASS III) investigators tested the efficacy and safety of alteplase administered between 3 and 4.5 hours after the onset of a stroke.1 After excluding patients with intracranial hemorrhage or major ischemic stroke, patients were randomized in a doubleblind fashion to receive treatment with intravenous (IV) alteplase or placebo. The primary end point was disability at 90 days with either a favorable outcome (modified Rankin Scale [mRS] 0-1) or unfavorable outcome (mRS 2-6). The secondary end point was a global outcome assessment combining 4 neurologic and disability scores. Safety outcomes included death, symptomatic intracerebral emorrhage (ICH), and other serious adverse events.
Date 2013-02-11
Language eng
Format video/mp4
Format Creation application/video
Type Image/MovingImage
Source 2013 North American Neuro-Ophthalmology Society Annual Meeting
Relation is Part of NANOS 2013: Jorunal Club
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Rights Management Copyright 2013. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s66m6dnb
Context URL The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/
Contributor Primary Bhatti, MT
Contributor Secondary Prasad, Sashank
Setname ehsl_novel_nam
ID 184416
Reference URL https://collections.lib.utah.edu/ark:/87278/s66m6dnb
Back to Search Results