A Comparison of Clinical Features of Pseudotumor Cerebri Secondary to Tetracyclines and Idiopathic Intracranial Hypertension

Pseudotumor cerebri (PTC) is a syndrome characterized by increased intracranial pressure with normal brain parenchyma, including absence of hydrocephalus, mass lesion, and underlying infection or malignancy. The primary form of PTC, idiopathic intracranial hypertension (IIH), accounts for the majority of cases. A variety of secondary causes have been identified, including PTC due to tetracycline antibiotics (PTC-T). We hypothesize that there are important clinical differences between these two groups.