| Identifier |
20140304_nanos_sciplatform2_02-1 |
| Title |
HE3286 Suppression of Experimental Optic Neuritis |
| Creator |
Shindler, Kenneth S; Khan, Reas S; Dine, Kimberly; Ahlem, Clarence |
| Subject |
Optic Nerve Inflammation; Optic Nerve Demyelination; Axonal Loss; Optic Neuritis; Corticosteroids; HE3286 Treatment |
| Description |
Optic nerve inflammation, demyelination and axonal loss are all prominent features of optic neuritis. While corticosteroids can hasten visual recovery in optic neuritis, no treatment is available to improve visual outcomes. HE3286, a synthetic derivative of a natural steroid, exerts anti-inflammatory effects in several disease models, and has purported direct neuroprotective effects as well. The ability of HE3286 to suppress optic neuritis in the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis was examined. |
| Date |
2014-03-04 |
| Language |
eng |
| Format |
application/pdf |
| Format Creation |
application/PowerPoint |
| Type |
Text |
| Source |
2014 North American Neuro-Ophthalmology Society Annual Meeting |
| Relation is Part of |
NANOS 2014: Scientific Platform Presentations (Session 2) |
| Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
| Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
| Rights Management |
Copyright 2013. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s67m3fqt |
| Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
| Contributor Primary |
Fiona Costello |
| Contributor Secondary |
Valerie Biousse |
| Setname |
ehsl_novel_nam |
| ID |
184021 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s67m3fqt |
