Optic Nerve-Pettern Electroretinogram

Identifier 19840118_nanos_sciplatform1_06
Title Optic Nerve-Pettern Electroretinogram
Creator Kuppersmith, Mark J
Subject Optic Nerve; Pattern Electroretinogram; Optic Neuropathies; Tumors; Optic Neuritis
Description Recently, the electroretinogram (ERG) recorded in response to patterned stimuli (PERG) were shown to be sensitive to pattern contrast and spatial frequency unlike the diffuse flash ERG. These findings coupled with experimental animal work suggest that the PERG reflects functioning of the ganglion cells which are the cell bodies of the axon of the optic nerve. Subjects with optic neuropathies should be ideally suited to this hypothesis. PERG, flash ERG, and visual evoked potentials (VEP) were studied in cases with unilateral optic nerve diseases secondary to tumors or optic neuritis. The PERG was absent in the affected eyes with poor acuity (less than 20/60) while the flash ERG was normal. A second group with acuity better than 20/40 showed reductions in the PERG amplitude of the affected compared to the normal eye. These interocular differences were especially marked when pattern contrast was reduced. Such results underscore the diagnostic value of the PERG in detecting mildly affected cases of optic nerve disease. These findings provide additional evidence regarding the ganglion cell origin of the PERG.
Relation is Part of NANOS 1984: Platform Presentations (Session I)
Contributor Primary Wirtschafter, Jonathan D
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Date 1984-01-18
Type Text
Format application/pdf
Format Creation application/pdf
Source 1984 North American Neuro-Ophthalmology Society Annual Meeting
Rights Management North American Neuro-Ophthalmology Association (NANOS), Copyright 1984. For further information regarding the rights to this collection, please visit http://library.med.utah.edu/NOVEL/about/copyright
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Collection Neuro-Ophthalmology Virtual Education Library: NOVEL, NANOS Annual Meeting, https://novel.utah.edu/collection/NAM/index/
Language eng
ARK ark:/87278/s67h4r82
Setname ehsl_novel_nam
Date Created 2014-03-21
Date Modified 2014-03-21
ID 183634
Reference URL https://collections.lib.utah.edu/details?id=183634
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