Platform Presentation: The SIRT1 Activator SRT501 Attenuates Retinal Ganglion Cell Loss and Preserves Axonal Function During Acute Optic Neuritis

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Identifier 20070212_nanos_platform_01.pdf
Title Platform Presentation: The SIRT1 Activator SRT501 Attenuates Retinal Ganglion Cell Loss and Preserves Axonal Function During Acute Optic Neuritis
Creator Shindler, Kenneth S; Ventura, Elvira; Elliott, Peter; Rostami, A. M.
Subject Optic Neuritis; Multiple Sclerosis; Retinal ganglion cells; Neuroprotection
Description Axonal damage and neuronal loss leads to permanent neurological disability in patients with multiple sclerosis (MS). Activation of SIRT1, an enzyme involved in cellular stress resistance and survival, can attenuate neuronal degeneration. The neuroprotective effects of SRT501, a SIRT1 activator, were examined during optic neuritis in experimental autoimmune encephalomyelitis (EAE), an animal model of MS.
Relation is Part of NANOS 2007: NANOS Platform Presentation
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Type Text
Format application/pdf
Format Creation application/pdf
Source 2007 North American Neuro-Ophthalmology Society Annual Meeting
Rights Management Copyright 2010. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Language eng
ARK ark:/87278/s6gx7hzk
Setname ehsl_novel_nam
Date Created 2011-07-06
Date Modified 2021-05-06
ID 180923
Reference URL https://collections.lib.utah.edu/ark:/87278/s6gx7hzk
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