Is it Naughty or Nice?

Update Item Information
Identifier walsh_2013_s2_c4-1
Title Is it Naughty or Nice?
Creator Daniel Gold, Madhura A. Tamhankar, Laura J. Balcer, MD, Professor, Department of Neurology, NYU Langone; Thomas Coyne, Clyde E. Markowitz, Steven L. Galetta, MD, NYU Langone
Subject Anterior optic neuritis; Ring-enhancing lesions; Fulminant MS
History Subjective fever and cold symptoms were noted 3 weeks prior, and she had experienced transient visual obscurations for 2 weeks.
Pathology Neuropathology showed vast areas of confluent demyelination, marked histiocytic infiltrates, perivascular lymphocytic cuffs, and numerous Creutzfeldt cells - suggestive of acute fulminant MS (Marburg variant), neuropathology did not show multifocal inflammation and demyelination centered around venous structures, which would be expected in ADEM.
Disease/Diagnosis Acute fulminant MS (Marburg disease)
Clinical Visual acuity was 20/400 OD and CF at 1 foot OS with dyschromatopsia, left RAPD and bilateral severe optic disc swelling with hemorrhages; large multifocal ringenhancinglesions with surrounding vasogenic edema centered around the gray-white junction, and bilateral opticnerve enhancement.
Presenting Symptom A 19-year-old woman presented with 4 days of rapidly progressive vision loss in both eyes associated with pain on eye movements.
Neuroimaging CT Scan; MRI
Date 2013-02-10
References Attached
Language eng
Format application/pdf
Type Text
Source 45th Annual Frank Walsh Society Meeting
Relation is Part of Case presented at the NANOS 2013 Walsh Session, February 10
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Holding Institution North American Neuro-Ophthalmology Association (NANOS), Copyright 2013. For further information regarding the rights to this collection, please visit http://library.med.utah.edu/NOVEL
ARK ark:/87278/s6031p23
Contributor Primary Kedar, Sachin
Contributor Secondary Rucker, Janet C
Setname ehsl_novel_fbw
ID 179159
Reference URL https://collections.lib.utah.edu/ark:/87278/s6031p23
Back to Search Results