| Identifier |
walsh_2007_s4_c5 |
| Title |
Horrible Hallucinations |
| Creator |
Melissa W. Ko, MD, FAAN, Upstate University Hospital |
| Subject |
Amino Acids, Peptides, and Proteins; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Polycystic Ovary Syndrome; Paraneoplastic Syndromes, Nervous System; Hallucinations; Teratoma |
| History |
A 34-year old female with a history of irritable bowel and polycystic ovarian syndrome. |
| Pathology |
Left adnexal ovarian mass with calcification; Hippocampal degeneration |
| Disease/Diagnosis |
Teratoma-associated encephalitis with antibodies to NMDA receptors |
| Clinical |
Episodes of paroxysmal facial grimacing, bilateral limb shaking, and abdominal contractions. |
| Presenting Symptom |
Headache; Seizures; Febrile; Hallucinations |
| Neuroimaging |
CT; MRI |
| Treatment |
Antipsychotic agents; Nootropic agents; Plasmaphoresis; Corticosteroids; Immunosupressive agents; Surgery |
| References |
1. Gultekin SH, Rosenfeld MR, Voltz R, et al. Paraneoplastic limbic Encephalitis: neurological symptoms, immunological findings and tumor association in 50 patients. Brain 2000; 123:1481-1494. 2. Vitaliani R, Mason W, Ances B et al. Paraneoplastic encephalitis, psychiatric symptoms, and hypoventilation in ovarian teratoma. Ann Neurol 2005; 58: 594-604. 3. Dalmau J, Tuzun E, Masjuan J, et al. Teratoma-associated Encephalitis with Antibodies to NMDA receptors. Ann Neurol (submitted). 4. Taylor RB, Mason W, Kong K. et al. Reversible paraneoplastic encephalomyelitis: associated with a benign ovarian teratoma. Can J Neurol Sci 1999; 26: 317-320. 5. Stein-Wexler R, Wootton-Gorges SL, Greco CM, Brunberg JA.Paraneoplastic limbic encephalitis in a teenage girl with an immature ovarian teratoma. Pediatr Radiol; 35: 694-697. |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
39th Annual Frank Walsh Society Meeting |
| Relation is Part of |
Case 5, Session 4, Walsh Session, NANOS 2007 |
| Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
| Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
| Rights Management |
Copyright 2008. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s62v2jws |
| Contributor Primary |
Ko, Melissa W. |
| Contributor Secondary |
Galetta, Steven; Baccon, Jennifer; Baliff, Jeffrey; Sansing, Lauren; Tüzün, Erdem; Dalmau, Josep |
| Setname |
ehsl_novel_fbw |
| ID |
178329 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s62v2jws |
