| Identifier |
walsh_2001_s5_c3 |
| Title |
"I Can't Read" |
| Creator |
Paul H. Phillips |
| Subject |
DNA, Mitochondrial; Optic Atrophy, Hereditary, Leber; Scotoma; Hyperemia |
| History |
A 7-year old male with bilateral blurred vision. |
| Pathology |
Enlarged optic chiasm; Hyperemic optic disc |
| Disease/Diagnosis |
Leber's hereditary optic neuropathy |
| Clinical |
VA: 20/60 OD, 20/300 OS; Color plates: 8/14 OD, 3/14 OS |
| Presenting Symptom |
Blurred vision OU |
| Neuroimaging |
CT; MRI |
| Treatment |
Corticosteroids |
| Date |
2001 |
| References |
1. Newman NJ. Leber's hereditary optic neuropathy: new genetic considerations. Arch Neurol 1993;50:540-8. 2. Newman NJ, Lott MT, Wallace DC. The clinical characteristics of pedigrees of Leber's Hereditary Optic neuropathy with the 11778 mutation. American Journal of Ophthalmology 1991;111:750-762. 3. Mashima Y, Oshitari K, Imamura Y, et al. Orbital high resolution magnetic resonance imaging with fast spin echo in the acute stage of Leber's hereditary optic neuropathy. J Neurol Neurosurg Psychiatry 1998;64:124-127. 4. Kermode AG, Moseley IF, Kendall BE, et al. Magnetic resonance imaging in Leber's optic neuropathy. J Neurol Neurosurg Psychiatry 1989;52:671-674. 5. Riordan-Eva P, Sanders MD, Govan GG, et al. The clinical features of Leber's hereditary optic neuropathy defined by the presence of a pathogenic mitochondrial DNA mutation. Brain 1995;118:319-337. 6. Smith JL, Tse DT, Byrne SF, et al. Optic nerve sheath distention in Leber's optic neuropathy and the significance of the "Wallace mutation." J Clin Neuro-ophthalmol 1990;10:231-238. 7. Wilson DR, Kline LB. Letter to the editor. J Clin Neuro-ophthalmol 1992;12:73-4. 8. Vaphiades MS, Newman NJ. Optic nerve enhancement on orbital magnetic resonance imaging in Leber's hereditary neuropathy. Journal of Neuro-Ophthalmology 1999;19:238-239. 9. Weiner NC, Newman NJ, Lessell S, et al. Atypical Leber's hereditary optic neuropathy with molecular confirmation. Arch Neurol 1993;50:470-473. 10. Raaf JE, Bair HL. Leber's disease: report of four cases in one family. Am J Ophthalmol 1938;21:384-389. 11. Imachi J, Nishizaki K. Neurosurgical treatment of Leber's optic atrophy. Folia Ophthalmol Jpn. 1970;21:209-217. |
| Language |
eng |
| Format |
application/pdf |
| Type |
Text |
| Source |
27th Annual North American Neuro-Ophthalmology Society Meeting, Frank B. Walsh Session CD-ROM |
| Relation is Part of |
Case 3, Session V, Walsh Session, NANOS 2001 |
| Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
| Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
| Rights Management |
Copyright 2008. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6g73hff |
| Contributor Primary |
Phillips, Paul H. |
| Contributor Secondary |
Glasier, Charles M. |
| Setname |
ehsl_novel_fbw |
| ID |
177699 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6g73hff |
