Idiopathic Intracranial Hypertension and Anemia: A Matched Case-Control Study

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Title Idiopathic Intracranial Hypertension and Anemia: A Matched Case-Control Study
Creator Weijie Violet Lin, Shauna Berry, Mohammad Obadah Nakawah, Ama Sadaka, Andrew G. Lee
Affiliation Departments of Medicine, Surgery, and Pediatrics (WVL), Santa Clara Valley Medical Center, Stanford University Hospitals, San Jose, California; Blanton Eye Institute (SB, AS, AGL), Houston Methodist Hospital, Houston, Texas; Houston Methodist Neurological Institute (MON), Houston Methodist Hospital, Houston, Texas; Departments of Ophthalmology (AGL), Neurology, and Neurosurgery, Weill Cornell Medical College, New York, New York; Department of Ophthalmology (AGL), Utah Medical Branch, Galveston, Texas; Department of Ophthalmology (AGL), Utah Maryland Anderson Cancer Center, Houston, Texas; Department of Ophthalmology (AGL), Baylor College of Medicine, Houston, Texas; Department of Ophthalmology (AGL), Center for Space Medicine, Houston, Texas; Department of Ophthalmology (AGL), Texas A&M College of Medicine, College Station, Texas; and Department of Ophthalmology (AGL), University of Iowa Hospitals and Clinics, Iowa City, Iowa
Abstract Background: An association between idiopathic intracranial hypertension (IIH) and anemia has been speculated from previous case reports and case series. Retrospective studies to date have not used matched case controls to compare standardized complete blood count (CBC) values for the presence of anemia. Methods: At our tertiary care facility, 50 patients with IIH were matched with 50 case-control patients to compare CBC values from laboratory affiliates with standardized ranges. Results: No significant difference was found for any CBC parameters for IIH vs control patients. For female IIH and control patients as well as male IIH patients, values for red blood cell count, hemoglobin (HGB), and hematocrit (HCT) tended to trend on the lower end of "normal" range, whereas this was not seen in male control patients. Conclusions: In this retrospective, matched case-control study, no significant association was found between IIH and anemia when comparing standardized CBC values. In accordance with previous studies, the prevalence of anemia may be relatively higher in the IIH population due to a prominent demographic overlap of females of child-bearing age.
OCR Text Show
Publisher Lippincott, Williams & Wilkins
Date 2020-06
Type Text
Source Journal of Neuro-Ophthalmology, June 2020, Volume 40, Issue 2
Language eng
Rights Management © North American Neuro-Ophthalmology Society
Publication Type Journal Article
ARK ark:/87278/s6pp4w37
Setname ehsl_novel_jno
Date Created 2020-09-14
Date Modified 2021-05-06
ID 1592875
Reference URL https://collections.lib.utah.edu/ark:/87278/s6pp4w37
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