Identifier |
20200309_nanos_sciplatform1_03-pdf |
Title |
Efficacy and Safety of Satralizumab from Two Phase 3 Trials in Neuromyelitis Optica Spectrum Disorder (PDF) |
Creator |
Benjamin Frishberg, Jerome de Seze, Brian Weinshenker, Yusuke Terada, Yuichi Kawata, Athos Gianella-Borradori, H. Christianvon Büdingen, Gaelle Klingelschmitt, Anthony Traboulsee, Takashi Yamamura |
Subject |
Optic Neuritis, Neuro-ophth & Systemic Disease (eg. MS, MG, Thyroid), Optic Nerve Trauma and Treatment, Non-Organic Visual Disorders, Miscellaneous |
Description |
Satralizumab is a humanized recycling monoclonal antibody that binds to the interleukin-6 (IL-6) receptor; IL-6 has been implicated in the pathophysiology of neuromyelitis optica spectrum disorder (NMOSD). Satralizumab was evaluated in patients with NMOSD in two Phase 3 studies: SAkuraSky (NCT02028884) and SAkuraStar (NCT02073279). In this analysis, we assessed the efficacy and safety of satralizumab in the individual study and pooled patient populations, including the subgroup of patients who were seropositive foraquaporin-4 immunoglobulin G (AQP4-IgG). |
Date |
2020-03 |
Language |
eng |
Format |
application/pdf |
Source |
2020 North American Neuro-Ophthalmology Society Annual Meeting |
Relation is Part of |
NANOS Annual Meeting 2020: Scientific Platform Session I |
Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
Rights Management |
Copyright 2020. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
ARK |
ark:/87278/s6nw4tv1 |
Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
Contributor Primary |
Benjamin M. Frishberg, MD |
Contributor Secondary |
Jerome de Seze, Brian Weinshenker, Yusuke Terada, Yuichi Kawata, Athos Gianella-Borradori, H. Christianvon Büdingen, Gaelle Klingelschmitt, Anthony Traboulsee, Takashi Yamamura |
Setname |
ehsl_novel_nam |
ID |
1543325 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6nw4tv1 |