Relationship Between Optic Nerve Angle, Intracranial Pressure, and Visual Outcomes in Idiopathic Intracranial Hypertension (IIH)

The tortuosity of the optic nerve can be quantified radiologically by measuring the angle of optic nerve deformation (ONA). In IIH patients, lowering the intracranial pressure (ICP) to a normal range by lumbar puncture (LP) leads to straightening of the optic nerve and an increase in the measured ONA on MRI. It is uncertain if ONA can be used as a marker of ICP or if a relationship between ONA and visual function exists. The objective of this study was to determine the ONA in patients with and without IIH, and to explore the relationship between ONA, CSF-opening pressure (CSF-OP) on LP, and visual function.