Methods to Assess Ocular Motor Dysfunction in Multiple Sclerosis

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Title Methods to Assess Ocular Motor Dysfunction in Multiple Sclerosis
Creator Christy K. Sheehy, MS, PhD, Alexandra Beaudry-Richard, Ethan Bensinger, Jacqueline Theis, OD, Ari J. Green, MD, MCR
Affiliation Department of Neurology (CKS, AB-R, JHS, AJG), University of California, San Francisco, San Francisco, California; School of Medicine (AB-R), University of Ottawa, Ottawa, Ontario, Canada; School of Optometry (EB, JT), University of California, Berkeley, Berkeley, California; Vision Science Graduate Group (EB), University of California, Berkeley, Berkeley, California; and Department of Ophthalmology (AJG), University of California, San Francisco, San Francisco, California
Abstract Multiple sclerosis (MS) is an inflammatory disease of the central nervous system causing the immune-mediated demyelination of the brain, optic nerve, and spinal cord and resulting in ultimate axonal loss and permanent neurological disability. Ocular motor dysfunction is commonly observed in MS but can be frequently overlooked or underappreciated by nonspecialists. Therefore, detailed and quantitative assessment of eye movement function has significant potential for optimization of patient care, especially for clinicians interested in treating visual symptoms or tracking disease progression. METHODS:: A brief history of eye tracking technology followed by a contextualized review of the methods that can be used to assess ocular motor dysfunction in MS-including a discussion of each method's strengths and limitations. We discuss the rationale for interest in this area and describe new tools capable of tracking eye movements as a possible means of monitoring disease. RESULTS/CONCLUSIONS:: This overview should inform clinicians working with patients with MS of how ocular motor deficits can best be assessed and monitored in this population. It also provides a rationale for interest in this field with insights regarding which techniques should be used for studying which classes of eye movements and related dysfunction in the disease.
OCR Text Show
Publisher Lippincott, Williams & Wilkins
Date 2018-12
Type Text
Source Journal of Neuro-Ophthalmology, December 2018, Volume 38, Issue 4
Language eng
Rights Management © North American Neuro-Ophthalmology Society
Publication Type Journal Article
ARK ark:/87278/s6rn88r3
Setname ehsl_novel_jno
Date Created 2020-01-08
Date Modified 2020-03-16
ID 1500773
Reference URL https://collections.lib.utah.edu/ark:/87278/s6rn88r3
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