The Stressed Optic Nerve at High Altitude and Treatment with Chemical Chaperon

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Identifier 20190319_nanos_sciplatform3_06_slides
Title The Stressed Optic Nerve at High Altitude and Treatment with Chemical Chaperon
Creator Yaping (Joyce) Liao, Alexandra Camargo, Matthew Dardet, Varun Kumar, Mohammad Shariati, Roopa Dalal, Vinicio de Jesus Perez, Louise Mesentier-Louro
Subject Optic Neuropathy
Description High altitude-associated non-arteritic anterior ischemic optic neuropathy (NAION) [1-3] typically occurs in younger patients who have disc-at-risk and few other risk factors [4-9], raising the possibility that hypobaric hypoxia may be the tipping point of vision loss. In this study, we investigated the effects of systemic hypoxia on the retina and optic nerve and assessed the therapeutic potential of pre-treatment with chemical chaperon 4-phenylbutyric acid (4- PBA), which reduces endoplasmic reticulum (ER) stress.
Relation is Part of NANOS 2019: Scientific Platform III
Contributor Primary Yaping (Joyce) Liao
Contributor Secondary Alexandra Camargo, Matthew Dardet, Varun Kumar, Mohammad Shariati, Roopa Dalal, Vinicio de Jesus Perez, Louise Mesentier-Louro
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Date 2019-03
Format application/pdf
Source 2019 North American Neuro-Ophthalmology Society Annual Meeting
Rights Management Copyright 2019. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Language eng
ARK ark:/87278/s67q3k77
Setname ehsl_novel_nam
Date Created 2019-09-10
Date Modified 2019-09-10
ID 1455038
Reference URL https://collections.lib.utah.edu/ark:/87278/s67q3k77
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