Amnion-derived Multipotent Progenitor Cells Attenuate Optic Nerve and Spinal Cord Demyelinating Disease

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Identifier 20190319_nanos_sciplatform3_03_slides
Title Amnion-derived Multipotent Progenitor Cells Attenuate Optic Nerve and Spinal Cord Demyelinating Disease
Creator Kenneth Shindler, Reas Khan, Kimberly Dine, Ahmara Ross, Keirnan Willett, Rick Banas, Larry Brown
Subject Neuro-Ophth & Systyemic Disease (eg. MS, MG, Thyroid), Optic Neuropathy, Demeylinating Disease
Description ST266 is the biological secretome of Amnion-derived Multipotent Progenitor (AMP) cells. ST266 proteins accumulate in eyes and optic nerves following intranasal delivery, resulting in selective suppression of optic neuritis in the experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis, without suppressing spinal cord lesions. We tested the hypothesis that systemic AMP cell administration could suppress both optic neuritis and myelitis in EAE.
Relation is Part of NANOS 2019: Scientific Platform III
Contributor Primary Kenneth Shindler
Contributor Secondary Reas Khan, Kimberly Dine, Ahmara Ross, Keirnan Willett, Rick Banas, Larry Brown
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Date 2019-03
Format application/pdf
Source 2019 North American Neuro-Ophthalmology Society Annual Meeting
Rights Management Copyright 2019. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Language eng
ARK ark:/87278/s6n05tc5
Setname ehsl_novel_nam
Date Created 2019-09-10
Date Modified 2019-09-10
ID 1455035
Reference URL https://collections.lib.utah.edu/ark:/87278/s6n05tc5
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