| Identifier |
20190319_nanos_posters_151 |
| Title |
Inhibition of glutamate carboxypepptidase II protects retinal ganglionic cell death induced by ischemia-reperfusion in rat |
| Creator |
Kyong Jin Cho, Bong-hui Kang, Jae-il Kim |
| Subject |
Optic Neuropathy |
| Description |
Excessive glutamate receptor activation is thought to be involved in retinal ganglion cell (RGC) death after ischemia- reperfusion damage. Glutamate carboxypeptidase II (GCPII) is an enzyme responsible for the hydrolysis of the neurotransmitter NAAG (N-acetyl-aspartyl-glutamate) to N-acetyl-aspartate and glutamate. Thus, in this study, we examined the effect of 2-(phosphonomethyl) pentanedioic acid (2-PMPA), a GCPII inhibitor, on RGC survival after acute high IOP ischemia-reperfusion damage. |
| Date |
2019-03 |
| Language |
eng |
| Format |
application/pdf |
| Source |
2019 North American Neuro-Ophthalmology Society Annual Meeting |
| Relation is Part of |
NAM 2019: Poster Session II: Scientific Advancements in Neuro-Ophthalmology |
| Collection |
Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu |
| Publisher |
Spencer S. Eccles Health Sciences Library, University of Utah |
| Holding Institution |
North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416 |
| Rights Management |
Copyright 2019. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright |
| ARK |
ark:/87278/s6cc5j7c |
| Context URL |
The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/ |
| Contributor Primary |
Kyong Jin Cho |
| Contributor Secondary |
Bong-hui Kang, Jae-il Kim |
| Setname |
ehsl_novel_nam |
| ID |
1432633 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6cc5j7c |
