Characterization of Visual Pathway Abnormalities in Infants with Congenital Zika Syndrome Using CT and MRI

Congenital malformations related to Zika virus infection were first described in 2015 among infants born in the Pernambuco state of Brazil. The congenital Zika syndrome since has been further characterized to include microcephaly, ocular abnormalities, arthrogryposis, and spinal cord thinning. Additionally, severe visual impairment has been demonstrated in affected infants, often in the absence of ocular abnormalities. However, to our knowledge, there has not been a comprehensive characterization of visual pathway abnormalities in these patients. The purpose of this study is to characterize visual pathway abnormalities in the congenital Zika syndrome using MRI and CT.