Pendular Seesaw Nystagmus in a Patient With a Giant Pituitary Macroadenoma: Pathophysiology and the Role of the Accessory Optic System

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Title Pendular Seesaw Nystagmus in a Patient With a Giant Pituitary Macroadenoma: Pathophysiology and the Role of the Accessory Optic System
Creator Peter Yat-Ming Woo; Saori Takemura; Allen Ming-Yan Cheong; Alberto Chi-Ho Chu; Yung Chan; Hoi-Tung Wong; Kwong-Yau Chan
Affiliation Department of Neurosurgery (PY-MW, ST, AC-HC, YC, H-TW, K-YC), Kwong Wah Hospital, Hong Kong, China; and School of Optometry (AM-YC), The Polytechnic University of Hong Kong, Hong Kong, China
Subject Seesaw Nystagmus; Giant Pituitary Macroadenoma; Accessory Optic System
Abstract Seesaw nystagmus is characterized by cyclic eye movements with a conjugate torsional component and a dissociated vertical component. In the first half of the cycle, one eye elevates and intorts, whereas the other eye depresses and extorts. The pattern is reversed in the remaining half of the cycle. We describe a patient with a giant pituitary adenoma who developed pendular seesaw nystagmus. Disturbance in the visuovestibular system is postulated to contribute to this form of seesaw nystagmus. Lesions compressing the optic chiasm and the accessory optic system could interrupt the transmission of retinal error signals to the inferior olivary nucleus and the interstitial nucleus of Cajal, thus interfering with the adaptive mechanism of the vestibulo-ocular reflex and leading to pendular seesaw nystagmus.
OCR Text Show
Publisher Lippincott, Williams & Wilkins
Date 2018-03
Type Text
Source Journal of Neuro-Ophthalmology, December 2018, Volume 38, Issue 1
Language eng
Rights Management © North American Neuro-Ophthalmology Society
Publication Type Journal Article
ARK ark:/87278/s62v6vbv
Setname ehsl_novel_jno
Date Created 2019-03-11
Date Modified 2019-03-11
ID 1404068
Reference URL https://collections.lib.utah.edu/ark:/87278/s62v6vbv
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