Ocular Motor Signs in Early Progressive Supranuclear Palsy

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Identifier Ocular_motor_signs_in_early_PSP
Title Ocular Motor Signs in Early Progressive Supranuclear Palsy
Alternative Title Video 4.38 Ocular motor signs in early progressive supra-nuclear palsy (PSP) from Neuro-Ophthalmology and Neuro-Otology Textbook
Creator Roksolyana Tourkevich, MD; Tony Brune, DO; Daniel R. Gold, DO
Affiliation (RT) Departments of Neurology, Otolaryngology - Head & Neck Surgery, The Johns Hopkins School of Medicine, Baltimore, Maryland; (TB) Department of Neurology, The Johns Hopkins School of Medicine, Baltimore, Maryland; (DRG) Departments of Neurology, Ophthalmology, Neurosurgery, Otolaryngology - Head & Neck Surgery, Emergency Medicine, and Medicine, The Johns Hopkins School of Medicine, Baltimore, Maryland
Subject Abnormal Saccades; Abnormal Convergence; Abnormal Pursuit; Abnormal Range; Abnormal VORS; Vertical Gaze Palsy; Downgaze Palsy; OMS Mesencephalon
Description 𝗢𝗿𝗶𝗴𝗶𝗻𝗮𝗹 𝗗𝗲𝘀𝗰𝗿𝗶𝗽𝘁𝗶𝗼𝗻: This is a 64-year old man who experienced imbalance and falls (usually backwards) for the last 6 months. He experienced difficulty navigating stairs and had become a messy eater (thought to be in large part due to his vertical gaze palsy), and had developed hypophonia. Exam demonstrated square wave jerks, supranuclear downward>upward palsy (i.e., improved with the vertical vestibulo-ocular reflex [VOR]), slow and hypometric horizontal saccades with very slow down>up saccades (especially apparent with optokinetic tape), convergence insufficiency, and saccadic smooth pursuit and VOR suppression. ; While a supranuclear vertical gaze palsy is the most sought after ocular motor finding when progressive supranuclear palsy (PSP) is being considered, other ocular motor abnormalities are commonly seen as well and include all of those listed above and seen in the video. Since upgaze can become impaired to some degree with normal aging (whether this is related to changes involving the orbital tissues or whether this is in part supranuclear is not clear), poor downgaze in a patient with a gait/balance disorder is more diagnostically meaningful. 𝗡𝗲𝘂𝗿𝗼-𝗼𝗽𝗵𝘁𝗵𝗮𝗹𝗺𝗼𝗹𝗼𝗴𝘆 𝗮𝗻𝗱 𝗡𝗲𝘂𝗿𝗼-𝗼𝘁𝗼𝗹𝗼𝗴𝘆 𝗧𝗲𝘅𝘁𝗯𝗼𝗼𝗸 𝗟𝗲𝗴𝗲𝗻𝗱: Exam demonstrated square wave jerks, supranuclear downward>upward palsy (i.e., improved with the vertical vestibulo-ocular reflex [VOR]), slow and hypometric horizontal saccades with very slow down>up saccades (especially apparent with optokinetic tape), convergence insufficiency, and saccadic smooth pursuit and VOR suppression. Since upgaze can become impaired to some degree with normal aging (whether this is related to changes involving the orbital tissues or whether this is in part supranuclear is not clear), poor downgaze in a patient with a gait/balance disorder is more diagnostically meaningful. (Video and legend created with the assistance of Dr. Roksolyana Tourkevich) https://collections.lib.utah.edu/ ark:/87278/s6gr0vxw
Date 2017-12
Language eng
Format video/mp4
Type Image/MovingImage
Collection Neuro-Ophthalmology Virtual Education Library: Dan Gold Neuro-Ophthalmology Collection: https://novel.utah.edu/Gold/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E SLC, UT 84112-5890
Rights Management Copyright 2016. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6gr0vxw
Setname ehsl_novel_gold
ID 1290930
Reference URL https://collections.lib.utah.edu/ark:/87278/s6gr0vxw
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