Saccadic pathways in the brainstem and cerebellum & mechanism for saccadic dysmetria in Wallenberg syndrome - Normal function of the brainstem/cerebellar saccadic pathways

Download item | Update item information
Identifier Saccadic_Dysmetria_Normal
Title Saccadic pathways in the brainstem and cerebellum & mechanism for saccadic dysmetria in Wallenberg syndrome - Normal function of the brainstem/cerebellar saccadic pathways
Subject Medulla OMS, Normal Saccades, Abnormal Saccades, Figures
Creator Daniel R. Gold, DO, Departments of Neurology, Ophthalmology, Neurosurgery, Otolaryngology - Head & Neck Surgery, The Johns Hopkins School of Medicine
Description The inferior cerebellar peduncle (ICP) carries climbing fibers to the dorsal vermis, and these fibers have an inhibitory influence over the Purkinje cells. These Purkinje cells normally inhibit the ipsilateral fastigial nucleus, and the fastigial nucleus projects to the contralateral inhibitory burst neurons (IBN) within the paramedian pontine reticular formation (PPRF). The IBN project contralaterally to inhibit the VIth nucleus to prevent unwanted saccades in this direction, while facilitating saccades (via the excitatory burst neurons [EBN]) in the opposite direction. Modified and redrawn with permission from Wolters Kluwer and the American Academy of Neurology. Frohman TC, Graves J, Balcer LJ, Galetta SL, Frohman EM. The neuro-ophthalmology of multiple sclerosis. Continuum (Minneap Minn) 2010;16:122-146.
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Date 2017
Format image/jpeg
Rights Management Copyright 2016. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Language eng
ARK ark:/87278/s6c8649n
Setname ehsl_novel_gold
Date Created 2017-08-14
Date Modified 2018-09-26
ID 1260093
Reference URL https://collections.lib.utah.edu/ark:/87278/s6c8649n
Back to Search Results