Debate Non-IOP Lowering Therapies Will be the Future of Glaucoma Management: Con

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Identifier 20150226_nanos_neurologyofglaucoma1_18
Title Debate Non-IOP Lowering Therapies Will be the Future of Glaucoma Management: Con
Description INTRODUCTION: Point-Counterpoint: IOP lowering therapies will always play a role in the future of glaucoma management. Lowering of intraocular pressure (IOP) either with medications or surgical interventions has been the mainstay of glaucoma therapy for well over 100 years and remains the only proven method to retard or prevent the development or progression of the disease. However, despite the fact that IOP lowering therapy is available, patients still may progress despite lowering of IOP. In addition, patients can develop glaucoma even at a low IOP. These findings have stimulated the development of alternate hypotheses regarding the pathogenesis of glaucomatous through non-IOP related mechanisms. There is clear evidence that vascular changes that alter perfusion to the optic nerve, changes in the supportive tissues of the lamina cribrosa, immunologic and excitotoxic/neurodegenerative changes all play an important role in the development of glaucoma. However I will argue in this debate that despite these insults, that IOP lowering therapy will always remain a valid and important treatment for glaucoma. This is because IOP load is integrally related to changes in the vasculature and the supportive cellular and connective tissue components of the lamina cribrosa and thus play a key role in the axogenic injury to the optic nerve that is critical to the development of glaucoma.
Date 2015-02-26
Language eng
Format video/mp4
Type Image/MovingImage
Relation is Part of 2015 North American Neuro-Ophthalmology Society Annual Meeting
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Holding Institution North American Neuro-Ophthalmology Association. NANOS Executive Office 5841 Cedar Lake Road, Suite 204, Minneapolis, MN 55416
Rights Management Copyright 2015. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6vh9g6b
Context URL The NANOS Annual Meeting Neuro-Ophthalmology Collection: https://novel.utah.edu/collection/NAM/toc/
Setname ehsl_novel_nam
ID 1253917
Reference URL https://collections.lib.utah.edu/ark:/87278/s6vh9g6b
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