Acetazolamide is commonly used to treat idiopathic intracranial hypertension (IIH) but there is insufficient information to establish an evidence base for its use.Objective: To determine whether acetazolamide is beneficial in improving vision when added to a low sodium, weight reduction diet in IIH patients with mild visual loss. Design: Multicenter randomized, double-masked, placebo-controlled study of acetazolamide in IIH participants with mild visual loss who are receiving a low sodium, weight reduction diet. Setting: Participants were enrolled at 38 academic and private practice sites in North America. Conclusions and Relevance: We found a statistically significant improvements in visual field function, quality of life measures, papilledema grade and CSF pressure in the acetazolamide group. We recommend using the maximally tolerated dosage of acetazolamide along with a low sodium weight reduction diet in IIH patients with mild visual loss.
Relation is Part of
NANOS Annual Meeting 2015 Sizzling Hot Topic: The IIHTT: What Have We Learned?
Spencer S. Eccles Health Sciences Library, University of Utah
2015 North American Neuro-Ophthalmology Society Annual Meeting