Opsoclonus provoked by convergence

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Identifier Opsoclonus_with_convergence
Title Opsoclonus provoked by convergence
Subject Abnormal Convergence, Opsoclonus
Creator Daniel R. Gold, DO, Departments of Neurology, Ophthalmology, Neurosurgery, Otolaryngology - Head & Neck Surgery, The Johns Hopkins School of Medicine
Description This is a 40-yo-man with post-infectious opsoclonus-myoclonus syndrome. Opsoclonus was intermittently evident in primary position, but was consistently provoked (and intensified) by convergence. Occasionally, opsoclonus (back-to-back saccades in horizontal, vertical, torsional planes without an intersaccadic interval) or ocular flutter (in the horizontal plane only) can be subtle or even difficult to distinguish from high frequency jerk nystagmus. However, these saccadic oscillations can be provoked with certain maneuvers such as eyelid closure (i.e., observing the corneal bulge under eyelids), following voluntary saccades, or with convergence. The underlying pathophysiology of opsoclonus/flutter is thought to involve damage to the pontine omnipause cells (dysfunction of the normal saccade-inhibiting circuitry) and/or disinhibition of the fastigial nucleus in the cerebellum (where the fastigial nucleus is part of the circuitry responsible for initiation of saccades).
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Date 2017
Type Image/MovingImage
Format video/mp4
Rights Management Copyright 2017. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E, SLC, UT 84112-5890
Collection Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu
Language eng
ARK ark:/87278/s6b02t5j
Setname ehsl_novel_gold
Date Created 2017-02-23
Date Modified 2018-01-22
ID 1209727
Reference URL https://collections.lib.utah.edu/ark:/87278/s6b02t5j
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