OCT Shows Different Relationships Between Macular Layers And Peripapillary RNFL In Acute Versus Chronic Papillitis And Papilledema

Optical coherence tomography (OCT) demonstrates swelling of the optic nerve head (ONH) and peripapillary retinal nerve fiber layer (P-RNFL) in patients with acute papilledema due to intracranial hypertension and in anterior optic neuritis (papillitis). As these conditions become chronic, atrophy of retinal ganglion cell (RGC) axons develops. We sought relationships between the P-RNFL and each layer of the macula in acute and chronic papillitis and compared them to eyes with papilledema.