Prevalence and Clinical Associations of Peripapillary Hyper-Reflective Ovoid Mass-Like Structures (PHOMS) in Patients with Craniosynostosis

Patients with craniosynostosis are at high risk of developing intracranial hypertension(IH) causing papilledema and secondary optic atrophy. Diagnosing and monitoring optic neuropathy-related vision loss can be challenging because many patients with craniosynostosis have cognitive delay limiting accuracy of testing and competing causes of vision loss. PHOMS are an optical coherence tomography(OCT) feature, possibly a marker of optic neuropathy. In this study, we investigated the prevalence of PHOMS in patients with craniosynostosis and its relationship with visual function and OCT parameters.