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Show IPECACUAN. IPECACUAN. boiling it becomes almost inert ; and the emetic propertyof ipe. . In hemorrhagies, when given in nauseating doses. . In profluvia, especially in dysentery ; so muchso, that it wasint esteemed a specific against that disease. But Cullen cacuan is most effectually counteracted by means ofthe acetic attributes its good effects, in this instance, to its producing a acid, insomuch that thirty grains of the powder, takenin two teady determination of the peristaltic motion of the intestines downwards, when given in repeated small doses. 7. In many spasmodic diseases; in epilepsy, asthma, dys. pnoea, pertussis, chronic diarrhea, hysteria, melancholy, mania. 8. In cachectic diseases, as in some kinds of dropsy. 9. In impetiginous diseases; in jaundice. 10. In local diseases ; in amaurosis, and several of the dysorexiz. 11. Lastly, in every instance when we wish to evacuate the stomach, as whenit is overloaded with food, or when poison, especially opium, has been swallowed. - use of ipecacuan, as an emetic, is contraindicated, Wherethere is a disposition to ham¢orrhagy. : Where there is an increased flow of blood towards the head. 5. In veryirritable subjects. 4, In pregnant women, and persons afflicted with hernia. Dr. Donald Monro has favoured us with thefoll owing judi. cious remarks on the employment of tthis drag. This root, says this experienced physician, is one of the mildest have fourid that the resinous part is more apt to act upon the intestinal canal, and to operate by stool By long-continued ounces of vinegar, produced only someloosestools. From these experiments it evidently appears that ipecacuan contains cinchonin andaresin, and that its emetic propertydoes not depend upon the latter, although we can scarcely attribute it to the former, as in ether substances it does not manifest any emetic property. It is therefore probably owing to some other principle soluble in water andalcohol. {EDICAL USE. Theprimaryeffect of ipecacuan is that of stimulating the stomach. If the dose besufficiently Jarge, it excites vomiting, by inverting the peristaltic motion of the stomach and duodenum; in a smaller dose it only produces nausea, and operatesbystool; and in still smaller doses it gently stimulates the stomach, increases the appetite, and facilitates digestion. Its secondaryef: fects depend on the sympathy of other parts with the stomach; and in this way only can weexplain its action as antispasmodic, diaphoretic, expectorant, and in checking hemorrhagies. Its beneficial effects, in some cases, also scem to be owing to the general concussion given to the whole system during the action of vomiting. Ipecacuan, properly administered, often proves serviceable, 1. In intermittent fevers. It has frequently succeededin stopping these, when given about an hour before an accession was expected, and also when given so as to produce vomiting at the time of an accession, orat the endof the cold stage. In continuedfevers. “We have never seen more decidedly beneficial effects from the use of any medicine whatever, than from the exhibition of ipecacuan in the commencement of typhus ever. An emetic, succeeded by a diaphoretic regimen, when administered paticinnthy early in the disease, very frequently cuts it short at once; and when it fails in this desirable object, it al- ways hasa beneficial influence on the progress ofthefever. 8. In inflammatory diseases, rheumatism. y ' 4. In exanthematous diseases, when the eruption is disposes to recede. and safest emetics we are acquainted with, and is employed as such from three or four grains to a scruple or half a drachm. It has likewise been greatly recommended in the cure of dysenteries, given in repeated small doses, from oneto three, four, five, or six grains, three or fourtimes in the day. But these small doses of ipecacuan, though they sometimes puke, and at other times keep up an increased discharge by stool, yet they seldom giveeffectual relief in the dysentery, not being strong enough to carry off those putrid corrupted huMowrs which are pent up within the bowels, and give rise to Many of the troublesome symptoms; besides, they generally keep up such a nausea, sickness, tremely difficult to prevail with and griping, that it is ex- patients to continue, even for a stort time, the use of this medicine given in this manner: and it 1 dysenteric merc cases I have always found it to answerbetter to sive a Scruple or halfa dr achm, or such dose as operated freely ie enctic, and afte peration to give afull dose of some |